Marc Wegener

No ORCID on file · 3 papers in corpus · active 2020-2026

Study types

  • other 2
  • article 1

Condition tags

  • endometriosis 1
  • adenomyosis 1
article 2026
Endometrial Hyperplasia Risk Is Increased by High-Fat Diet Via Estrogen-Driven Stromal Fibroblast Reprogramming Toward a Pro-Fibrotic State
·doi:10.64898/2026.03.20.713224

Abstract The uterine endometrium is capable of scarless regeneration under coordinated estrogen and progesterone signaling across the menstrual cycle. Obesity suppresses progesterone production, leading to chronic estrogen exposure and incr…

other 2020
ARID1A Mutations Promote P300-Dependent Endometrial Invasion through Super-Enhancer Hyperacetylation
Cell reports ·doi:10.1016/j.celrep.2020.108366

Endometriosis affects 1 in 10 women and is characterized by the presence of abnormal endometrium at ectopic sites. ARID1A mutations are observed in deeply invasive forms of the disease, often correlating with malignancy. To identify epigene…

other 2020
SWI/SNF inactivation in the endometrial epithelium leads to loss of epithelial integrity
Human molecular genetics ·doi:10.1093/hmg/ddaa227

Although ARID1A mutations are a hallmark feature, mutations in other SWI/SNF (SWItch/Sucrose Non-Fermentable) chromatin remodeling subunits are also observed in endometrial neoplasms. Here, we interrogated the roles of Brahma/SWI2-related g…