Ting Xie

No ORCID on file · 2 papers in corpus

lab-animal 2022

Mechanical stress influences the morphology and function of human uterosacral ligament fibroblasts and activates the p38 MAPK pathway

International urogynecology journal ·doi:10.1007/s00192-021-04850-7

INTRODUCTION AND HYPOTHESIS: Pelvic organ prolapse (POP) is a common condition in older women that affects quality of life. Mechanical injury of the pelvic floor support system contributes to POP development. In our study, we aimed to exami…

lab-animal 2022

The protective effect of 17 β-estradiol on human uterosacral ligament fibroblasts from postmenopausal women with pelvic organ prolapse

Frontiers in physiology ·doi:10.3389/fphys.2022.980843

This study aims to explore the protective effects of 17 β-estradiol on the human uterosacral ligament fibroblasts (hUSLFs) under static or stretched conditions. The experiments were performed on hUSLFs derived from pelvic organ prolapse (PO…