Jastrzebski JP

ORCID: 0000-0001-8699-7742 · 3 papers in corpus
lab-animal 2024
Immunomodulatory dynamics in the porcine myometrium: global transcriptome analysis, including the effects of PPARγ ligands
BMC genomics ·doi:10.1186/s12864-024-11083-7

BACKGROUND: The myometrium is involved in many processes during pregnancy and the estrous/menstrual cycle. Peroxisome proliferator-activated receptors (PPARs) can be regulators of the processes occurring in the myometrium. In the present st…

lab-animal 2022
PPARγ regulates the expression of genes involved in the DNA damage response in an inflamed endometrium
Scientific reports ·doi:10.1038/s41598-022-07986-8

Inflammation is a biological response of the immune system, which can be triggered by many factors, including pathogens. These factors may induce acute or chronic inflammation in various organs, including the reproductive system, leading to…

lab-animal 2020
The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the transcriptome of aryl hydrocarbon receptor (AhR) knock-down porcine granulosa cells
PeerJ ·doi:10.7717/peerj.8371

BACKGROUND: 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a toxic man-made chemical, adversely affecting reproductive processes. The well-characterized canonical mechanism of TCDD action involves the activation of aryl hydrocarbon receptor …