Rebecca C. Arend

ORCID: 0000-0003-2108-3426 · 6 papers in corpus
2025
Pilot Study of Daily Exemestane in Women with Endometrial Intraepithelial Neoplasia or Low-Grade Endometrial Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research ·doi:10.1158/1078-0432.ccr-25-1878

PurposeTo evaluate exemestane, an aromatase inhibitor, as a preventive intervention for endometrial cancer.Experimental designThis is a multicenter, single-arm, "window of opportunity" pilot study of exemestane (25 mg daily for 21-42 days) …

article 2024
A spatial proteomic study of platinum-refractory, high-grade serous ovarian cancer implicates dual AKT and WNT activity linked to an immunosuppressive tumor microenvironment
·doi:10.1016/j.ygyno.2024.07.119
article 2020
Large, Non-Cavity Distorting Intramural Leiomyomas Decrease Leukemia Inhibitory Factor in the Secretory Phase Endometrium
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-019-00056-x

Despite mounting evidence that large intramural leiomyomas decrease fecundity during in vitro fertilization cycles, few studies have demonstrated a mechanism for this impact. We hypothesize that large intramural leiomyomas (IM) decrease the…

2018
Histone Methyltransferase EZH2: A Therapeutic Target for Ovarian Cancer.
Molecular cancer therapeutics ·doi:10.1158/1535-7163.mct-17-0437

Ovarian cancer is the fifth leading cause of cancer-related deaths in females in the United States. There were an estimated 22,440 new cases and 14,080 deaths due to ovarian cancer in 2017. Most patients present with advanced-stage disease,…

2010
Co-expression of GPR30 and ERbeta and their association with disease progression in uterine carcinosarcoma.
American journal of obstetrics and gynecology ·doi:10.1016/j.ajog.2010.04.046

ObjectiveWe sought to evaluate the expression of G protein-coupled receptor 30 (GPR30) and estrogen receptor (ER)beta in uterine carcinosarcoma (CS).Study designImmunohistochemistry was performed using antibodies to GPR30, ERbeta, ERalpha, …

article 2009
Extragenital adenosarcoma: A case report, review of the literature, and management discussion
Gynecologic Oncology ·doi:10.1016/j.ygyno.2009.07.033

BackgroundMüllerian adenosarcoma is a rare mixed epithelial-mesenchymal tumor. An extragenital site of origin and sarcomatous overgrowth are associated with aggressive clinical behavior.CaseWe present a rare case of extragenital adenosarcom…