Schneider G

ORCID: 0000-0001-6706-1084 · 3 papers in corpus
2018
Antiproliferative Properties of Newly Synthesized 19-Nortestosterone Analogs Without Substantial Androgenic Activity.
Frontiers in pharmacology ·doi:10.3389/fphar.2018.00825

19-Nortestosterone C-17 epimers with prominent antiproliferative properties have been previously described. In our present study, five novel 17α-19-nortestosterones (3-7) were synthesized to increase their beneficial biological activities w…

2014
Role of pharmacoepidemiology studies in addressing pharmacovigilance questions: a case example of pancreatitis risk among ulcerative colitis patients using mesalazine.
European journal of clinical pharmacology ·doi:10.1007/s00228-014-1660-7

PurposeWell-designed pharmacoepidemiology studies address several limitations of postmarketing spontaneous reports in regard to signal evaluation. This study evaluated a signal of disproportionate reporting of acute pancreatitis cases obser…

2008
Domain organization of long signal peptides of single-pass integral membrane proteins reveals multiple functional capacity.
PloS one ·doi:10.1371/journal.pone.0002767

Targeting signals direct proteins to their extra- or intracellular destination such as the plasma membrane or cellular organelles. Here we investigated the structure and function of exceptionally long signal peptides encompassing at least 4…