Yulia Nefedova

ORCID: 0000-0002-5121-9294 · 2 papers in corpus

lab-animal 2023

975 Activation of myeloid cells by β-glucan clears disseminating ovarian cancer cells from the peritoneal fluid through macrophage-mediated clotting and omentum neutrophil extracellular traps

·doi:10.1136/jitc-2023-sitc2023.0975

Background Ovarian cancer (OvCa) is the most lethal gynecological cancer and the fifth leading cause of cancer-related deaths in women. Despite an initial positive response to therapy, most patients relapse and present with chemotherapy res…

lab-animal 2022

Protection of Regulatory T Cells from Fragility and Inactivation in the Tumor Microenvironment

Cancer immunology research ·doi:10.1158/2326-6066.cir-22-0295

Fragility of regulatory T (Treg) cells manifested by the loss of neuropilin-1 (NRP1) and expression of IFNγ undermines the immune suppressive functions of Treg cells and contributes to the success of immune therapies against cancers. Intrat…