Jihong Yang

No ORCID on file · 6 papers in corpus
lab-animal 2026
Cell death & disease ·doi:10.1038/s41419-026-08886-9

Metabolic determinants of oocyte quality and embryonic development remain incompletely understood. Here, we profiled metabolites in human cumulus cells (CCs) and follicular fluid (FF), validated in two mouse models, and integrated transcrip…

lab-animal 2025
FASEB journal : official publication of the Federation of American Societies for Experimental Biology ·doi:10.1096/fj.202500914r

The accelerating trend of obesity in women of childbearing age has become a significant issue in personal health, female fecundity, and offspring development. Simvastatin (SV) is a statin commonly prescribed oral agent for lipid-lowering th…

observational 2025
Frontiers in endocrinology ·doi:10.3389/fendo.2025.1679860

BACKGROUND: The objective of this study was to assess the trade-off between cycle continuation and cancellation in slow ovarian response (SOR) patients, and to evaluate the impact of SOR on embryo developmental potential and clinical pregna…

lab-animal 2022
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-022-00938-x

BACKGROUND: Nicotinamide (NAM) is an important antioxidant, which is closely related to female fertility, but its role has not been clearly elucidated. The purpose of the present study was to investigate the effects of NAM on follicular dev…

observational 2022
Communications biology ·doi:10.1038/s42003-022-03710-4

In order to investigate the metabolic characteristics of human follicular fluid (FF) and to reveal potential metabolic predictors of follicular development (FD) with clinical implications, we analyzed a total of 452 samples based on a two-s…

nonrandomized-trial 2020
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-020-00631-x

BACKGROUND: To investigate the metabolic profiles in the follicular fluid (FF) samples from patients undergoing in vitro fertilization (IVF) and to analyze the correlations with follicular development. METHODS: The FF samples were obtained…