Sphingolipids are important constituents of cell membranes, which play key roles as regulatory molecules for various cellular functions. Sphingosine-1-phosphate produced by sphingosine kinase 1 (SPHK1) promotes cell proliferation, regulates…
Membrane proteins of the claudin superfamily are important components of cellular tight and adherens junctions. Although their exact function remains unclear, these proteins may play a role in tissue remodeling, a process which is associate…
Cytokeratins are a multigene family of polypeptides expressed in distinct combinations along the various routes of epithelial differentiation. In endometrial cancer and cervical intraepithelial neoplasia/cervical squamous cell carcinoma, th…
OBJECTIVE: To characterize the expression of WNT7A in human eutopic and ectopic endometrium. DESIGN: Experimental study using real-time polymerase chain reaction, laser microdissection, in situ hybridization, and immunofluorescence. SETTI…
BACKGROUND: The metalloproteinases (MMPs) are a family of proteolytic enzymes involved in tissue remodeling and cell migration. Endometrial tissue remodeling proceeds during the menstrual cycle and requires a temporary and spatially balance…
ObjectiveTo illustrate the influence of pregnancy on primary umbilical endometriosis.DesignCase report.SettingGynecologic endocrinology outpatient department of a university hospital.Patient(s)27-year-old nulliparous woman.Intervention(s)Su…
ObjectiveTo compare the expression of genes playing a decisive role during the embryonic development of the female genital tract (WNT4, WNT5A, WNT7A, PAX8) in the peritoneum of patients with endometriosis and control patients.DesignExperime…