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Gonadotropin-releasing hormone (GnRH) antagonists inhibit estrogen synthesis and secretion, making them promising treatment options for estrogen-dependent diseases, such as endometriosis. This study developed a population pharmacokinetic/ph…
Objective: The prevalence of steatotic liver disease (SLD) is rising globally, while endometriosis is a leading cause of infertility. Although links with metabolic syndrome have been reported, its relationship with SLD remains unclear. We …
BackgroundMetabolic dysfunction-associated steatohepatitis (MASH) is characterized by persistent inflammatory cascades, with macrophage activation playing a pivotal role. Chitinase 1 (CHIT1), produced by activated macrophages, is a key play…
PurposeTo evaluate the effect of degree of necrosis after uterine artery embolization (UAE) on symptom recurrence at midterm clinical follow-up in patients with adenomyosis.Materials and methodsWomen (N = 50) who underwent UAE for symptomat…