Narendra P. Singh

ORCID: 0000-0002-2443-7157 · 2 papers in corpus

article 2023

Estrobolome dysregulation is associated with altered immunometabolism in a mouse model of endometriosis

Frontiers in endocrinology ·doi:10.3389/fendo.2023.1261781

INTRODUCTION: Endometriosis is a painful disease that affects around 5% of women of reproductive age. In endometriosis, ectopic endometrial cells or seeded endometrial debris grow in abnormal locations including the peritoneal cavity. Commo…

2019

AhR Activation Leads to Massive Mobilization of Myeloid-Derived Suppressor Cells with Immunosuppressive Activity through Regulation of CXCR2 and MicroRNA miR-150-5p and miR-543-3p That Target Anti-Inflammatory Genes.

Journal of immunology (Baltimore, Md. : 1950) ·doi:10.4049/jimmunol.1900291

The compound 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), an environmental contaminant, is a potent ligand for aryl hydrocarbon receptor (AhR). In the current study, we made an exciting observation that naive C57BL/6 mice that were exposed i…