Baziyar P

ORCID: 0000-0001-7487-3662 · 1 paper in corpus

2025

Inhibitory effect of Fisetin against the aggregation process of SOD1 E100K mutant: computer-based drug design as a potential therapeutic for ALS disease.

Frontiers in chemistry ·doi:10.3389/fchem.2025.1569777

Protein misfolding and aggregation in superoxide dismutase 1 (SOD1) are linked to the neurodegenerative disease amyotrophic lateral sclerosis (ALS). SOD1 mutations have a significant role in the pathophysiology and fast behavior of protopat…