Rugang Zhang

ORCID: 0000-0002-7255-2360 · 11 papers in corpus
2025
Cancer research ·doi:10.1158/0008-5472.can-25-0654

Subunits of the SWI/SNF chromatin remodeling complex are altered in ∼20% of human cancers. Exemplifying the alterations is the ARID1A mutation that occurs in ∼50% of ovarian clear-cell carcinoma (OCCC), a disease with limited therapeutic op…

article 2025
·doi:10.1158/0008-5472.30699610

Supplementary figures and table

article 2024
·doi:10.1158/1538-7445.ovarian23-ia009

Abstract The past decade has brought unprecedented progress in understanding the genetics of epithelial ovarian cancer (EOC), but cures remain elusive due to the lack of insights into mechanisms that can be leveraged to develop new therapie…

article 2023
·doi:10.1136/jitc-2023-sitc2023.0975

Background Ovarian cancer (OvCa) is the most lethal gynecological cancer and the fifth leading cause of cancer-related deaths in women. Despite an initial positive response to therapy, most patients relapse and present with chemotherapy res…

preprint 2023
·doi:10.1158/0008-5472.c.6514212

AbstractOvarian clear cell carcinoma (OCCC) is a deadly and treatment-resistant cancer, which arises within the unique microenvironment of endometriosis. In this study, we identified a subset of endometriosis-derived mesenchymal stem cells …

preprint 2023
·doi:10.1158/0008-5472.c.6514212.v1

AbstractOvarian clear cell carcinoma (OCCC) is a deadly and treatment-resistant cancer, which arises within the unique microenvironment of endometriosis. In this study, we identified a subset of endometriosis-derived mesenchymal stem cells …

preprint 2023
·doi:10.1158/0008-5472.22432671

Supplementary figures and table

preprint 2023
·doi:10.1158/0008-5472.22432671.v1

Supplementary figures and table

other 2022
Cancer research ·doi:10.1158/0008-5472.CAN-22-1294

UNLABELLED: Ovarian clear cell carcinoma (OCCC) is a deadly and treatment-resistant cancer, which arises within the unique microenvironment of endometriosis. In this study, we identified a subset of endometriosis-derived mesenchymal stem ce…

2018
Expert review of precision medicine and drug development ·doi:10.1080/23808993.2018.1503050
review 2018
Molecular cancer research : MCR ·doi:10.1158/1541-7786.MCR-18-0368

Ovarian cancer remains the most lethal gynecologic malignancy in the developed world. Despite the unprecedented progress in understanding the genetics of ovarian cancer, cures remain elusive due to a lack of insight into the mechanisms that…