Kulkarni A

No ORCID on file · 7 papers in corpus · active 2004-2025

Study types

  • other 1
  • review 1

Condition tags

  • endometriosis 2
  • dysmenorrhea 1
  • infertility 1
2025
Shear-Stress Initiates Signal Two of NLRP3 Inflammasome Activation in LPS-Primed Macrophages through Piezo1.
ACS applied materials & interfaces ·doi:10.1021/acsami.4c18845

The innate immune system is tightly regulated by a complex network of chemical signals triggered by pathogens, cellular damage, and environmental stimuli. While it is well-established that changes in the extracellular environment can signif…

2023
The avoiding late diagnosis of ovarian cancer (ALDO) project; a pilot national surveillance programme for women with pathogenic germline variants in BRCA1 and BRCA2.
Journal of medical genetics ·doi:10.1136/jmg-2022-108741

BackgroundOur study aimed to establish 'real-world' performance and cost-effectiveness of ovarian cancer (OC) surveillance in women with pathogenic germline BRCA1/2 variants who defer risk-reducing bilateral salpingo-oophorectomy (RRSO).Met…

2023
UK consensus recommendations for clinical management of cancer risk for women with germline pathogenic variants in cancer predisposition genes: RAD51C, RAD51D, BRIP1 and PALB2.
Journal of medical genetics ·doi:10.1136/jmg-2022-108898

Germline pathogenic variants (GPVs) in the cancer predisposition genes BRCA1, BRCA2, MLH1, MSH2, MSH6, BRIP1, PALB2, RAD51D and RAD51C are identified in approximately 15% of patients with ovarian cancer (OC). While there are clear guideline…

other 2023
Vaginoscopic Resection of Oblique Vaginal Septum in OHVIRA Syndrome Before Menarche
Journal of minimally invasive gynecology ·doi:10.1016/j.jmig.2023.01.019

OBJECTIVE: To demonstrate vaginoscopic resection of the oblique vaginal septum in a girl with Obstructed Hemi Vagina and Ipsilateral Renal Agenesis (OHVIRA) syndrome before menarche. DESIGN: Stepwise demonstration of surgical technique wit…

2022
Acidic ascites inhibits ovarian cancer cell proliferation and correlates with the metabolomic, lipidomic and inflammatory phenotype of human patients.
Journal of translational medicine ·doi:10.1186/s12967-022-03763-3

BackgroundThe poor prognosis of ovarian cancer patients is strongly related to peritoneal metastasis with the production of malignant ascites. However, it remains largely unclear how ascites in the peritoneal cavity influences tumor metabol…

2021
The similarities and differences between mesonephric carcinoma and mesonephric-like carcinoma: Two cases.
Gynecologic oncology reports ·doi:10.1016/j.gore.2021.100856

•Mesonephric carcinomas are rare cancers that arise from mesonephric remnants.•Mesonephric-like carcinomas are similar but with mesonephric differentiation.•These cases add to the limited literature of these separate but similar entities.

review 2004
Spontaneous Rupture of the Uterine Vessels in Pregnancy
Obstetrics and gynecology ·doi:10.1097/01.aog.0000121833.79081.c7

In Brief BACKGROUND: Hemoperitoneum resulting from spontaneous rupture of the uterine vessels in pregnancy is rare and associated with high maternal and fetal mortality. CASE: A woman presented with acute abdominal pain and hypovolemic shoc…