Heath JK

ORCID: 0000-0003-4886-4070 · 2 papers in corpus

2005

The production of interleukin-11 and decidualization are compromised in endometrial stromal cells derived from patients with infertility.

The Journal of clinical endocrinology and metabolism ·doi:10.1210/jc.2004-0868

IL-11 signaling is critical for decidualization of the endometrial stroma in early pregnancy in the mouse. In this study, we investigate the function of IL-11 signaling in cAMP-induced decidualization of human endometrial stromal cells. We …

2003

Functional characterization of W147A: a high-affinity interleukin-11 antagonist.

Endocrinology ·doi:10.1210/en.2002-0144

IL-11 is a member of the gp130 family of cytokines, which signal via assembly of multisubunit receptor complexes containing at least one molecule of the transmembrane signaling receptor gp130. IL-11 forms a high-affinity complex, thereby in…