Jinyi Tong

Adenomyosis is a common gynecological disorder that causes heavy menstrual bleeding and chronic pelvic pain. Progestin-based therapy is widely used for long-term management, but irregular uterine bleeding frequently occurs and severely affe…

OBJECTIVE: Approximately 20% of adenomyosis cases occur in women under 40 years of age [1]. Although LNG-IUD is the first-line medical therapy, its treatment failure is closely associated with uterine volume [2] with expulsion rates reporte…

Quasi-targeted metabolomics was employed to investigate the effects of PC knockdown (si#1) on cellular metabolite profiles, with experimental analysis performed by Novogene. The workflow consisted of four main phases: sample collection, met…

Quasi-targeted metabolomics was employed to investigate the effects of PC knockdown (si#1) on cellular metabolite profiles, with experimental analysis performed by Novogene. The workflow consisted of four main phases: sample collection, met…

RESEARCH QUESTION: Does pyruvate carboxylase drive the progression of endometriosis, and, if so, what is the underlying mechanism? DESIGN: The expression of pyruvate carboxylase in clinical endometrial specimens was examined via immunohist…

Abstract Endometriosis is a chronic inflammatory disease driven by progressive fibrosis, yet the functional roles of adhesion molecules E-selectin and ICAM1 in mediating the inflammation–fibrosis axis remain poorly defined. This study aimed…

Endometriosis is a chronic gynecological disorder defined by the growth of endometrial-like tissue outside the uterus, driven by estrogen-dependent inflammation and progressive fibrosis. According to available data, remodeling and persisten…

STUDY OBJECTIVE: To evaluate the feasibility and effectiveness of hysteroscopic suture fixation of the levonorgestrel-releasing intrauterine system (LNG-IUS) for the treatment of adenomyosis. DESIGN: A retrospective case series. SETTING: …

BACKGROUND: Placement of a levonorgestrel-releasing intrauterine system (LNG-IUS) is an effective treatment for adenomyosis, especially for patients who have severe dysmenorrhea symptoms but a strong desire to preserve fertility. Nonetheles…

OBJECTIVE: To introduce an effective approach using the hysteroscopic cold-knife surgery system (HCSS) for suture fixation of the levonorgestrel-releasing intrauterine device (LNG-IUD) in patients with adenomyosis. DESIGN: Video descriptio…