Chris J. van Koppen (11724227)

No ORCID on file · 2 papers in corpus · active 1753

Study types

  • article 1
  • dataset 1

Condition tags

  • endometriosis 2
dataset 1753
Potent Dual\nInhibitors of Steroid Sulfatase and 17β-Hydroxysteroid\nDehydrogenase Type 1 with a Suitable Pharmacokinetic Profile for In Vivo Proof-of-Principle Studies in an Endometriosis Mouse\nModel
·doi:10.1021/acs.jmedchem.3c00571.s001

Treating estrogen-dependent diseases like endometriosis\nwith drugs\nsuppressing local estrogen activation may be superior to existing\nendocrine therapies. Steroid sulfatase (STS) and 17β-hydroxysteroid\ndehydrogenase type 1 (17β-HSD1) are…

article 1753
Potent Dual\nInhibitors of Steroid Sulfatase and 17β-Hydroxysteroid\nDehydrogenase Type 1 with a Suitable Pharmacokinetic Profile for In Vivo Proof-of-Principle Studies in an Endometriosis Mouse\nModel
·doi:10.1021/acs.jmedchem.3c00571.s002

Treating estrogen-dependent diseases like endometriosis\nwith drugs\nsuppressing local estrogen activation may be superior to existing\nendocrine therapies. Steroid sulfatase (STS) and 17β-hydroxysteroid\ndehydrogenase type 1 (17β-HSD1) are…