Lou S

No ORCID on file · 2 papers in corpus · active 2024-2025
2025
Iron metabolism disorder promotes postovulatory oocyte aging by inducing oxidative stress damage.
Life medicine ·doi:10.1093/lifemedi/lnaf032

Reactive oxygen species (ROS) involve in oocyte postovulatory aging, yet the mechanism of ROS accumulation is not fully understood. We explored iron metabolic status and its relationship with ROS in mouse oocytes during postovulatory aging …

2024
Iron accumulation in ovarian microenvironment damages the local redox balance and oocyte quality in aging mice.
Redox biology ·doi:10.1016/j.redox.2024.103195

Accumulating oxidative damage is a primary driver of ovarian reserve decline along with aging. However, the mechanism behind the imbalance in reactive oxygen species (ROS) is not yet fully understood. Here we investigated changes in iron me…