Sofia Lamas

ORCID: 0000-0002-1665-1989 · 3 papers in corpus
other 2025
Metformin reverses infertility in a mouse model of endometriosis: unveiling disease pathways and implications for future clinical approaches
Reproductive BioMedicine Online ·doi:10.1016/j.rbmo.2024.104474

RESEARCH QUESTION: Does metformin reverse endometriosis-associated infertility? DESIGN: Endometriosis was induced by transplanting uterus fragments from B6CBAF1 mice into recipients of the same strain. The mice were divided into groups: en…

article 2024
P-331 Unlocking metformin’s potential: exploring its impact on inflammation and oxidative pathways in an endometriosis mouse model
·doi:10.1093/humrep/deae108.695

Abstract Study question Could endometriosis-associated pro-oxidative and pro-inflammatory condition be mitigated by metformin? Summary answer Metformin treatment tends to reduce fibrosis in ectopic tissues, while up-regulating anti-oxidativ…

article 2021
P–300 Metformin: new therapeutic approach for endometriosis-associated infertility
·doi:10.1093/humrep/deab130.299

Abstract Study question Could endometriosis-associated infertility be mitigated by metformin? Summary answer Metformin treatment restored fertility to control rates in endometriosis-induced mice that present lower fertility. No effect was o…