Hapgood JP

ORCID: 0000-0002-4414-4861 · 1 paper in corpus

2022

Differential off-target glucocorticoid activity of progestins used in endocrine therapy.

Steroids ·doi:10.1016/j.steroids.2022.108998

The glucocorticoid receptor (GR) regulates transcription of genes involved in multiple processes. Medroxyprogesterone acetate (MPA), widely used in the injectable contraceptive Depo-MPA (DMPA), has off-target effects via the GR, which may r…