Caihong Zheng

ORCID: 0009-0000-1588-242X · 7 papers in corpus
other 2025
Scientific reports ·doi:10.1038/s41598-025-93146-7

Endometriosis and Recurrent Implantation Failure (RIF) are both pivotal clinical issues within the realm of reproductive medicine, sharing significant overlap in their pathophysiological mechanisms. However, research exploring the commonali…

lab-animal 2024
Acta biomaterialia ·doi:10.1016/j.actbio.2024.09.037

Endometriosis seriously affects 6-10 % of reproductive women globally and poses significant clinical challenges. The process of ectopic endometrial cell colonization shares similarities with cancer, and a dysfunctional immune microenvironme…

lab-animal 2024
Drug delivery and translational research ·doi:10.1007/s13346-024-01661-3

Mifepristone, a progesterone receptor antagonist, was initially used to terminate early pregnancy. As scientific research advanced, it emerged to be effective in the treatment of various tumors and tumor-like conditions such as endometriosi…

lab-animal 2022
Frontiers in bioengineering and biotechnology ·doi:10.3389/fbioe.2022.918368

This investigation probed endometriosis treatment using targeted nanoparticles (NPs) to modulate autophagic activity. To that end, a novel form of polymer-based NP gene delivery platform consisting of polyethyleneimine (PEI) conjugated to s…

lab-animal 2019
International journal of nanomedicine ·doi:10.2147/ijn.s224579

BACKGROUND: Ovarian cancer is a common malignancy in the female reproductive system with a high mortality rate. The most important reason is multidrug resistance (MDR) of cancer chemotherapy. To reduce side effects, reverse resistance and i…

lab-animal 2016
International journal of nanomedicine ·doi:10.2147/ijn.s99692

To identify a new drug candidate for treating endometriosis which has fewer side effects, a new polymeric nanoparticle gene delivery system consisting of polyethylenimine-grafted chitosan oligosaccharide (CSO-PEI) with hyaluronic acid (HA) …

lab-animal 2012
Biomaterials ·doi:10.1016/j.biomaterials.2011.09.077

To reduce the side effects and improve the lack of clinical treatment countermeasures in endometriosis chemotherapy, a polymeric micelle gene delivery system composed of lipid grafted chitosan micelles (CSO-SA) and the pigment epithelium de…