Guan D

ORCID: 0000-0001-8800-3158 · 3 papers in corpus
2025
Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure.
Cell proliferation ·doi:10.1111/cpr.70037

Natural killer (NK) cells are critical regulators of immune processes during early pregnancy, playing a key role in maintaining maternal-foetal immune tolerance and supporting successful implantation. In particular, uterine NK cells, a spec…

2025
Integrative single-cell transcriptomics of sheep ovarian development reveals dynamic transcriptional programs relevant to reproductive traits.
iScience ·doi:10.1016/j.isci.2025.112422

Sheep (Ovis aries) are valuable biomedical models for studying human reproductive biology, however, the transcriptional dynamics underlying their ovarian development remain insufficiently characterized. In this study, we profiled 61,649 sin…

2022
Emerging trends and frontier research on recurrent implantation failure: a bibliometric analysis.
Annals of translational medicine ·doi:10.21037/atm-22-703

BackgroundRecurrent implantation failure (RIF) has been recognized to be a major obstacle to the successful application of artificial reproduction technologies. In this study, the trends in RIF research were examined through a bibliometric …