Robert A. Soslow

ORCID: 0000-0002-7269-5898 · 32 papers in corpus
nonrandomized-trial 2023
Gynecologic Oncology ·doi:10.1016/j.ygyno.2023.06.021

OBJECTIVE: Gynecologic cancers are traditionally managed according to their presumed site of origin, without regard to the underlying histologic subtype. Clear cell histology is associated with chemotherapy refractoriness and poor survival.…

other 2023
Gynecologic Oncology ·doi:10.1016/j.ygyno.2023.06.579

OBJECTIVES: To evaluate clinical, laboratory, and radiological variables from preoperative contrast-enhanced computed tomography (CECT) for their ability to distinguish ovarian clear cell carcinoma (OCCC) from non-OCCC and to develop a nomo…

case-report 2023
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists ·doi:10.1097/pgp.0000000000000935

Gynecologic carcinomas with RAS mutations may show a wide spectrum of histologic types, including mixed types. We present the case of a 63-yr-old patient diagnosed with an ovarian tumor harboring a mesonephric-like adenocarcinoma in a backg…

observational 2022
The American journal of surgical pathology ·doi:10.1097/pas.0000000000001863

Cervical clear cell carcinoma (CCC) is a rare human papillomavirus-independent adenocarcinoma. While recent studies have focused on gastric-type endocervical adenocarcinoma (GTA), little is known about CCC. A total of 58 (CCCs) were collect…

other 2022
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc ·doi:10.1038/s41379-022-01160-1

Mullerian adenosarcoma is an uncommon mesenchymal tumor of the gynecologic tract. Most cases are low-grade, while high-grade adenosarcomas are rare and not well studied. Herein, we characterize the clinicopathologic and molecular features o…

review 2021
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists ·doi:10.1097/pgp.0000000000000751

The incidence of endocervical adenocarcinoma, the second most common cervical cancer in the world, has been on the rise. While most cervical cancers are squamous cell carcinomas and associated with high-risk oncogenic human papillomavirus (…

other 2019
The American journal of surgical pathology ·doi:10.1097/pas.0000000000001095

The current World Health Organization (WHO) classification for endocervical adenocarcinoma (EA) is based on descriptive morphologic characteristics; however, it does not fully reflect our current knowledge of the diverse pathogenesis of cer…

review 2019
Virchows Archiv : an international journal of pathology ·doi:10.1007/s00428-019-02601-0

Endocervical adenocarcinomas (ECAs) are currently classified according to the 2014 World Health Organization (WHO) system, which is predominantly based on descriptive morphologic characteristics, considers factors bearing minimal etiologica…

observational 2019
Gynecologic Oncology ·doi:10.1016/j.ygyno.2018.10.033

OBJECTIVE: Determining whether carcinomas concurrently involving endometrium and ovary are independent primary tumors (IPTs) or endometrial carcinomas with ovarian metastases (at least stage IIIA endometrial cancers, IIIA-EC) using clinicop…

review 2018
Seminars in diagnostic pathology ·doi:10.1053/j.semdp.2017.11.007

Epithelial metastases originating from the gynecologic tract or secondarily involving it frequently display a different morphology when compared to the primary tumor. Furthermore, issues such as modes of metastasis, appropriate nomenclature…

other 2018
The American journal of surgical pathology ·doi:10.1097/pas.0000000000001090

The International Endocervical Adenocarcinoma Criteria and Classification was developed to separate endocervical adenocarcinomas (ECAs) into 2 main categories on the basis of morphology such as human papilloma virus-associated (HPVA) and no…

other 2018
The American journal of surgical pathology ·doi:10.1097/pas.0000000000000986

We sought to classify endocervical adenocarcinomas (ECAs) based on morphologic features linked to etiology (ie, human papillomavirus [HPV] infection), unlike the World Health Organization 2014 classification. The International Endocervical …

diagnostic-accuracy 2016
Abdominal radiology (New York) ·doi:10.1007/s00261-016-0998-y

PURPOSE: To assess the utility of morphologic and quantitative CT features in differentiating abdominal wall endometriosis (AWE) from other masses of the abdominal wall. METHODS: Retrospective IRB-approved study of 105 consecutive women fr…

2016
·doi:10.1016/j.ygyno.2016.04.406
other 2016
The American journal of surgical pathology ·doi:10.1097/pas.0000000000000556

Characteristic histopathologic features have been described in high-grade serous carcinoma associated with BRCA abnormalities (HGSC-BRCA), which are known to have relatively favorable clinical outcomes. The aim of this study was to evaluate…

observational 2016
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists ·doi:10.1097/pgp.0000000000000256

Many adnexal high-grade serous carcinomas (HGSCs) may derive from microscopic precursors in the fallopian tube. By studying a series of low-stage ovarian carcinomas, we anticipated that HGSCs would be distributed in a pattern suggesting sec…

review 2016
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc ·doi:10.1038/modpathol.2015.127

This review covers three areas in endometrial tumor pathology: International Federation of Gynecology and Obstetrics (FIGO) staging, the use of frozen section, and Lynch syndrome. The section on FIGO staging will emphasize problems that pra…

observational 2016
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society ·doi:10.1097/igc.0000000000000559

OBJECTIVE: The purpose of this study was to assess the rate of lymph node (LN) metastasis in comprehensively staged ovarian clear cell carcinoma (OCCC) clinically confined to the ovary and determine factors associated with LN metastasis. M…

2016
·doi:10.1016/j.ygyno.2016.04.328
observational 2015
The American journal of surgical pathology ·doi:10.1097/pas.0000000000000550

Ovarian endometrioid carcinomas (OEC) of low grade have characteristic morphologic features, but high-grade tumors can mimic high-grade serous and undifferentiated carcinomas. We reviewed tumors initially diagnosed as OEC to determine wheth…

other 2013
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society ·doi:10.1097/igc.0b013e3182a80ac8

OBJECTIVE: Risk-reducing salpingo-oophorectomy (RRSO) is recommended for women with BRCA mutation due to increased risk of pelvic serous carcinoma. Serous tubal intraepithelial carcinoma (STIC) is a pathologic finding of unknown clinical si…

observational 2013
The American journal of surgical pathology ·doi:10.1097/PAS.0b013e318272ff19

Current histologic criteria endorsed by World Health Organization for surface epithelial ovarian tumors suffer from less than optimal reproducibility and correlation with clinical outcomes. A modified approach for histologic subclassificati…

case-report 2013
·doi:10.14309/00000434-201310001-01255

Purpose: Endometrial cancer in the colon is rare. It usually arises from endometriosis, which can be seen by histological examination in proximity to the tumor. Women with Lynch syndrome (LS) are at an increased risk for endometrial cancer.…

other 2013
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists ·doi:10.1097/pgp.0b013e318273fd07

Many ovarian tumors, including high-grade serous carcinoma (HGSC), show clear cell change. Accurate diagnosis is important, however, as ovarian clear cell carcinoma (OCCC) is known to be less responsive to traditional types of ovarian cance…

observational 2013
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists ·doi:10.1097/pgp.0b013e31825f7c08

Robotic surgery is increasingly being performed for endometrial cancer. Robotic hysterectomies (RH), like traditional laparoscopic hysterectomies (LH), involve a significant amount of uterine manipulation. The use of a manipulator is though…