Jukka‐Pekka Mecklin

ORCID: 0000-0003-4895-2249 · 3 papers in corpus
observational 2017
Comparison of lifestyle, hormonal and medical factors in women with sporadic and Lynch syndrome-associated endometrial cancer: A retrospective case-case study
Molecular and clinical oncology ·doi:10.3892/mco.2017.1211

Data available on lifestyle-associated hormonal and medical factors among endometrial cancer (EC)-affected women who carry the Lynch Syndrome (LS) mutation is limited. The aim of the present retrospective case study was to compare the repro…

observational 2016
Endometrial cancer risk factors among Lynch syndrome women: a retrospective cohort study
British journal of cancer ·doi:10.1038/bjc.2016.193

BACKGROUND: Lynch syndrome (LS) is associated with a significant lifetime risk of endometrial cancer (EC). There are limited data on factors modifying the EC risk in LS patients. METHODS: The study cohort included 136 LS mutation-positive …

other 2014
Epigenetic analysis of sporadic and Lynch-associated ovarian cancers reveals histology-specific patterns of DNA methylation
Epigenetics ·doi:10.4161/15592294.2014.983374

Diagnosis and treatment of epithelial ovarian cancer is challenging due to the poor understanding of the pathogenesis of the disease. Our aim was to investigate epigenetic mechanisms in ovarian tumorigenesis and, especially, whether tumors …