Sikai Chen

ORCID: 0009-0007-8808-3910 · 9 papers in corpus
case-report 2026
·doi:10.21037/gpm-2025-1-57

Background: Abdominal wall endometriosis (AWE) is a relatively rare subtype of endometriosis that has the potential for malignant transformation. It typically presents with nonspecific clinical symptoms, such as abdominal pain and palpable …

case-report 2021
Chinese medical journal ·doi:10.1097/cm9.0000000000001734

To the Editor: Primary vaginal carcinoma is a rare malignant disease, which represents only approximately 1% to 2% of female genital malignancies. Vaginal adenosis is defined by the presence of metaplastic cervical or endometrial epithelium…

observational 2021
·doi:10.1016/j.gocm.2021.07.007

Abstract Background Endometriosis is a chronic disease that affects women in reproductive age, and adenomyosis was known as “endometriosis in the uterus”. Endometriosis is an immune-dysfunction-related disease, contributing to the diversity…

lab-animal 2020
Journal of pain research ·doi:10.2147/jpr.s232313

BACKGROUND: Pain sensitization processing in the central nervous system may be related to endometriosis-associated pain in patients. The purpose of this study was to understand the alterations in the abnormal pain response in central brain …

observational 2020
Archives of gynecology and obstetrics ·doi:10.1007/s00404-020-05657-5

BACKGROUND: Ovarian endometriosis is the most frequent type of endometriosis. Despite the use of surgery and medication, many patients suffer from recurrence within near future. Currently, there are no effective clinical characteristics ava…

2020
·doi:10.2147/jpr.s262383

[This corrects the article DOI: 10.2147/JPR.S232313.].

observational 2020
Annals of translational medicine ·doi:10.21037/atm-20-1309

BACKGROUND: Endometriosis is a benign, chronic, gynecological disease which affect the women in reproductive age. The dysfunction of immune system is associated with endometriosis and the diversity of microbiota in genital tract. According …

lab-animal 2019
Annals of translational medicine ·doi:10.21037/atm.2019.11.73

BACKGROUND: Endometriosis (EM) is a common gynecological disease in women of reproductive age. These patients in approximately 80% suffer the various degree pain. This study will investigate synergistically the mechanism of the higher-posit…

observational 2019
·doi:10.20944/preprints201911.0147.v1

Abstract Objective: Endometriosis is a chronic disease characterized by the growth of endometrial cells outside the uterine cavity. The dysfunction of the immune system is strongly associated with the progression of endometriosis, and is al…