Hugh S. Taylor

OBJECTIVES: To characterise contemporary trends in the hormonal management of endometriosis in adolescent and young adult patients with biopsy-proven endometriosis. METHODS: Retrospective chart review of women aged 14-25 years who underwen…

OBJECTIVE: To determine the impact of oral contraceptive (OC)-induced mood lability/depression on treatment maintenance in women with endometriosis. DESIGN: Women with endometriosis were retrospectively identified through International Cla…

Abstract Study question Can MRI provide a useful assessment of changes to endometrioma, DIE, and adenomyosis lesion burden resulting from QVR treatment? Summary answer MRI successfully measured changes in the number, size, diffusion, and pe…

Endometriosis is a debilitating, chronic inflammatory disease affecting approximately 10% of reproductive-age women worldwide with no cure. While macrophages have been intrinsically linked to the pathophysiology of endometriosis, targeting …

Currently, three crucial questions regarding the reliability of ovarian reserve measures in women with ovarian endometrioma during the reproductive age are being discussed. Firstly, the effects of endometriotic cystectomy on short and long-…

OBJECTIVE: To evaluate the efficacy and safety of 2 doses of vilaprisan vs. placebo in participants with symptomatic endometriosis. DESIGN: Multicenter, randomized, double-blind, placebo-controlled, parallel-group phase 2b trial (NCT035733…

Endometriosis is a chronic often painful disease associated with infertility, which often leads to diminished quality of life. Therefore, we sought to identify the characteristics of women with endometriosis, focusing on variables that refl…

A similar abstract of the interim analysis was previously published in Fertility and Sterility. EPIGALLOCATECHIN GALLATE (EGCG) FOR TREATMENT OF UNEXPLAINED INFERTILITY ASSOCIATED WITH UTERINE FIBROIDS (PRE-FRIEND TRIAL): EARLY SAFETY ASSES…

Gonadotropin-releasing hormone (GnRH) is central to the control of the entire hypothalamic-pituitary-gonadal axis. Manipulation of GnRH, in turn, regulates pituitary response and ovarian hormone production. Gonadotropin-releasing hormone an…

Endometriosis is a chronic inflammatory gynecological disorder regulated by estrogen and characterized by the growth of endometrial tissue outside the uterus. We have previously demonstrated that mesenchymal stem cells (MSCs) contribute dir…

IMPORTANCE: Endometriosis is a common chronic gynecologic pathology with a large negative impact on women's health. Beyond severe physical symptoms, endometriosis is also associated with several psychiatric comorbidities, including depressi…

ABSTRACT Endometriosis is a chronic gynecologic disease that causes pelvic pain and is often seen in association with depression and anxiety. The association with these mental health conditions was previously linked to chronic pain, althoug…

Consequences of the shift from the use of non-invasive testing for diagnosis to screening purposes • As the high-throughput screening and sequencing become increasingly faster and affordable, that there will be a swell of commercial non-inv…

dogma that aneuploidy in oocytes is exclusively caused by missegregation of chromosomes during meiosis I and II.Study funding/competing interest(s): Data was mined from a study funded by ESHRE.Illumina provided microarrays and other consuma…

IN VITRO: culturing of endometrial cells obtained from the uterine mucosa or ectopic sites is used to study molecular and cellular signalling relevant to physiologic and pathologic reproductive conditions. However, the lack of consensus on …

Despite the clinically recognized association between endometriosis and infertility, the mechanisms implicated in endometriosis-associated infertility are not fully understood. Endometriosis is a multifactorial and systemic disease that has…