OBJECTIVE: Precision medicine applications depend on elucidating the underlying molecular mechanisms of disease. However, many disorders, such as endometriosis, remain poorly characterised genetically due to data scarcity, positive-unlabell…
OBJECTIVE: Several endometrial preparation protocols are available in frozen-thawed embryo (FET) transfer cycles. The aim of this study was to compare the clinical outcomes, obstetrical and neonatal complications between ovulation disorder …
Deep neural networks have shown significant advancements in modelling complex non-linear relationships in high-dimensional biomedical data. Understanding the interplay between genetic variants and disease susceptibility is still a considera…
Adenomyosis (AM) is a common and challenging disease in gynecological clinics, which adversely affects women's physical and mental health. Despite the growing number of studies, the mechanisms associated with the growth of the lesion are po…
ETHNOPHARMACOLOGICAL RELEVANCE: Shaoyao Gancao Decoction (SGD) is a renowned traditional Chinese medicinal formulation widely utilized in Asia. It is particularly effective in treating spastic, painful, and inflammatory conditions, especial…
PURPOSE: The window of implantation (WOI) is a brief period during which the endometrium is receptive to embryo implantation. This study investigated the relationship between miR-135a-5p and endometrial receptivity. METHODS: Peripheral blo…
Intrauterine adhesion (IUA) is characterized by the formation of fibrous scar tissue within the uterine cavity, which significantly impacts female reproductive health and even leads to infertility. Unfortunately, severe cases of IUA current…
BACKGROUND: Endometriosis (EMS) is a gynecological disease defined by the translocation and growth of endometrial tissue in other tissues or organs outside the uterus. Its clinical manifestations are dysmenorrhea, irregular menstruation, an…
INTRODUCTION: Cancer antigen 125 (CA125) and human epididymis protein 4 (HE4) are biomarkers for ovarian cancer. Their specificity and sensitivity are often limited during pregnancy as a result of great fluctuations. The risk of ovarian mal…