Yanni Yu

ORCID: 0009-0002-4254-7680 · 2 papers in corpus

article 2017

The allosteric AKT inhibitor, MK2206, decreases tumor growth and invasion in patient derived xenografts of endometrial cancer

Cancer biology & therapy ·doi:10.1080/15384047.2017.1281496

The purpose of this study was to test the effect of MK2206, an allosteric inhibitor of AKT, on the growth and invasion of patient-derived xenografts (PDX) of endometrial cancer. Three PDX lines, USC1 (uterine serous), EEC2 (endometrioid gra…

article 2014

Activated AKT Pathway Promotes Establishment of Endometriosis

Endocrinology ·doi:10.1210/en.2013-1951

The pathogenesis of endometriosis remains unclear, and relatively little is known about the mechanisms that promote establishment and survival of the disease. Previously, we demonstrated that v-akt murine thymoma viral oncogene homolog (AKT…