Dong E

ORCID: 0000-0002-0654-0660 · 3 papers in corpus
2026
Multi-Omics Data Reveal Estrogen-Driven Dysregulation and Stromal-Epithelial Signaling Alterations in Endometrial Polyps.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology ·doi:10.1096/fj.202504234r

Endometrial polyps (EPs) are common uterine lesions associated with abnormal uterine bleeding and infertility, yet their pathogenesis remains poorly defined. Here, we performed single-cell RNA sequencing of normal endometrium, para-polyp, a…

2025
Single-cell sequencing uncovers disrupted stromal-macrophage communication as a driver of intrauterine adhesion progression.
Communications biology ·doi:10.1038/s42003-025-08634-3

Intrauterine adhesions (IUA), characterized by endometrial fibrosis, pose a serious threat to women's reproductive health, yet their molecular mechanisms remain poorly understood. Here, we use single-cell RNA sequencing (scRNA-seq) to profi…

2023
Generation of Human Endometrial Assembloids with a Luminal Epithelium using Air-Liquid Interface Culture Methods.
Advanced science (Weinheim, Baden-Wurttemberg, Germany) ·doi:10.1002/advs.202301868

The endometrial lining of the uterus is essential for women's reproductive health and consists of several different types of epithelial and stromal cells. Although models such as gland-like structures (GLSs) and endometrial assembloids (EnA…