Dongzhe Lei

ORCID: 0009-0005-6528-7131 · 1 paper in corpus

review

How is the "most bothersome symptom" construct measured across health conditions? A systematic review of patient-reported outcome measures

Patient related outcome measures ·doi:10.1080/1179271X.2026.2732841

OBJECTIVE: Patient-reported outcome measures (PROMs) capture patients' experiences and perspectives of symptoms. One approach involves measuring the "most bothersome symptom," an outcome recommended in some regulatory guidance and core outc…