Izquierdo JM

ORCID: 0000-0002-7942-4046 · 2 papers in corpus
review 2022
The Multifunctional Faces of T-Cell Intracellular Antigen 1 in Health and Disease
International journal of molecular sciences ·doi:10.3390/ijms23031400

T-cell intracellular antigen 1 (TIA1) is an RNA-binding protein that is expressed in many tissues and in the vast majority of species, although it was first discovered as a component of human cytotoxic T lymphocytes. TIA1 has a dual localiz…

review 2015
T-cell intracellular antigens in health and disease
Cell cycle (Georgetown, Tex.) ·doi:10.1080/15384101.2015.1053668

T-cell intracellular antigen 1 (TIA1) and TIA1-related/like protein (TIAR/TIAL1) are 2 proteins discovered in 1991 as components of cytotoxic T lymphocyte granules. They act in the nucleus as regulators of transcription and pre-mRNA splicin…