Carmen J. Williams

ORCID: 0000-0001-6440-7086 · 6 papers in corpus
2019
Molecular cancer research : MCR ·doi:10.1158/1541-7786.mcr-19-0475

Early-life exposure to estrogenic chemicals can increase cancer risk, likely by disrupting normal patterns of cellular differentiation. Female mice exposed neonatally to the synthetic estrogen diethylstilbestrol (DES) develop metaplastic an…

2018
Toxicologic pathology ·doi:10.1177/0192623318779326

Developmental exposure to estrogenic chemicals is an established risk factor for cancer of the female reproductive tract. This increase in risk has been associated with disruption of normal patterns of cellular differentiation during critic…

2017
Reproductive toxicology (Elmsford, N.Y.) ·doi:10.1016/j.reprotox.2016.07.011

Sex-specific differentiation, development, and function of the reproductive system are largely dependent on steroid hormones. For this reason, developmental exposure to estrogenic and anti-androgenic endocrine disrupting chemicals (EDCs) is…

2017
Environmental health perspectives ·doi:10.1289/ehp428

BackgroundEarly-life exposure to estrogenic compounds affects the development of the reproductive system in rodent models and humans. Soy products, which contain phytoestrogens such as genistein, are one source of exposure in infants fed so…

2016
Molecular cancer research : MCR ·doi:10.1158/1541-7786.mcr-16-0084

UnlabelledThe oncofetal protein sine oculis-related homeobox 1 (SIX1) is a developmental transcription factor associated with carcinogenesis in several human cancer types but has not been investigated in human endometrial cancer. In a model…

2015
eLife ·doi:10.7554/elife.10453

Development of uterine endometrial receptivity for implantation is orchestrated by cyclic steroid hormone-mediated signals. It is unknown if these signals are necessary for oviduct function in supporting fertilization and preimplantation de…