Diana Monsivais
ORCID: 0000-0001-5660-6392
· 39 papers in corpus
lab-animal
2016
Endometriosis is a gynecological disease defined by the extrauterine growth of endometrial-like cells that cause chronic pain and infertility. The disease is limited to primates that exhibit spontaneous decidualization, and diseased cells a…
lab-animal
2015
OBJECTIVE: To define the expression and function of DNA methyltransferases (DNMTs) in response to decidualizing stimuli in endometriotic cells compared with healthy endometrial stroma. DESIGN: Basic science. SETTING: University research c…
review
2015
Endometriosis has been initially described as the presence of ectopic endometrial tissue on pelvic organs or in extrapelvic sites; and this has been used as its key pathologic feature ever since. Endometriosis responds to fluctuations in es…
lab-animal
2014
In endometriosis, stromal and epithelial cells from the endometrium form extrauterine lesions and persist in response to estrogen (E2) and prostaglandin E2 (PGE2). Stromal cells produce excessive quantities of estrogen and PGE2 in a feed-fo…
lab-animal
2014
Endometriosis is a gynecological disease defined by the extrauterine growth of endometrial-like cells that cause chronic pain and infertility. The disease is limited to primates that exhibit spontaneous decidualization, and diseased cells a…
lab-animal
2012
OBJECTIVE: To define altered gene expression networks in endometriosis. DESIGN: Experiments using endometriotic tissues and primary cells. SETTING: Division of Reproductive Biology Research, Northwestern University. PATIENT(S): Premenopa…
2012
lab-animal
2012
Endometriosis is an estrogen-dependent gynecological disease that affects 6–10% of women of reproductive age. It is a major cause of chronic pelvic pain and infertility, and poses a heavy financial burden on society, with annual estimates t…
2012
lab-animal
2012
BACKGROUND: Progesterone, via its nuclear receptor (PR), exerts an overall tumorigenic effect on both uterine fibroid (leiomyoma) and breast cancer tissues, whereas the antiprogestin RU486 inhibits growth of these tissues through an unknown…
2012
Endometriosis is a benign gynecological disease causing infertility, adhesions and chronic pain in approximately 10% of reproductively-aged women due to the extrauterine growth of endometrial stromal and glandular cells. Endometriotic lesio…
2011
review
2011
Approximately half of women with endometriosis achieve pain relief from existing medical or surgical treatments. Medical treatments are usually directed at inhibiting estrogen action or its production from the ovaries and do not address loc…
2011