Riham Aboulesia

ORCID: 0000-0001-8883-068X · 1 paper in corpus

2023

Pharmacological or genetic inhibition of LTCC promotes cardiomyocyte proliferation through inhibition of calcineurin activity.

·doi:10.21203/rs.3.rs-3552794/v1

Abstract Cardiomyocytes (CMs) lost during ischemic cardiac injury cannot be replaced due to their limited proliferative capacity, which leads to progressive heart failure. Calcium (Ca2+) is an important signal transducer that regulates key…