Jiao Fan
ORCID: 0000-0002-7146-3753
· 6 papers in corpus
other
2026
Accurate pathway activity inference from single-cell RNA sequencing (scRNA-seq) data is hindered by sparsity, technical noise, and the weak yet coordinated nature of transcriptional programs. Existing methods typically aggregate expression …
observational
2026
BACKGROUND: Endometriosis (EM) may be associated with adverse pregnancy outcomes, but its relationship with gestational diabetes mellitus (GDM) and circulating metabolic biomarkers remains incompletely defined. This study evaluated temporal…
lab-animal
2025
Cellular senescence is known to be involved in tissue repair, but its role in adenomyosis remains unclear. This study was tasked to evaluate the expression of Klotho, a well-known aging-suppressing protein, as well as PPARγ and DNMT1 in ade…
lab-animal
2025
Endometriosis‑associated infertility is considered to be linked to cellular senescence. The present study assessed whether rapamycin, a senescence inhibitor, ameliorates endometriosis‑associated infertility by upregulating peroxisome prolif…
other
2023
RESEARCH QUESTION: Can rapamycin, used as an anti-senescence drug before IVF cycles, improve the IVF outcomes of women with endometriosis by reducing oxidative stress and senescence? DESIGN: This retrospective analysis involved 168 endomet…
observational
2017
Our purpose is to explore whether anti-dsDNA antibody, which was demonstrated to enter living cells and induced apoptosis, could adversely affect reproductive outcomes. A total of 259 women receiving the in vitro fertilization-embryo transf…