Joseph T Lundquist

No ORCID on file · 2 papers in corpus · active 2008-2010

Study types

  • other 2

Condition tags

  • endometriosis 2
other 2010
Synthesis and biological evaluation of piperazinyl heterocyclic antagonists of the gonadotropin releasing hormone (GnRH) receptor
Bioorganic & medicinal chemistry letters ·doi:10.1016/j.bmcl.2010.02.099

Antagonism of the gonadotropin releasing hormone (GnRH) receptor has resulted in positive clinical results in reproductive tissue disorders such as endometriosis and prostate cancer. Following the recent discovery of orally active GnRH anta…

other 2008
2-phenyl-4-piperazinylbenzimidazoles: orally active inhibitors of the gonadotropin releasing hormone (GnRH) receptor
Bioorganic & medicinal chemistry ·doi:10.1016/j.bmc.2008.05.024

Antagonism of the gonadotropin releasing hormone (GnRH) receptor has shown positive clinical results in numerous reproductive tissue disorders such as endometriosis, prostate cancer and others. Traditional therapy has been limited to peptid…