Sex hormones contribute to sexually dimorphic immunological outcomes, including the innate cytotoxic capacity of Natural Killer (NK) cells in populations of cisgender individuals, but has yet to be evaluated in transgender individuals. Here…
BACKGROUND: Endometriosis (EMs) is a chronic inflammatory disease characterized by ectopic endometrial growth. This study aimed to identify and analyze potential signatures of pyroptosis-related genes in EMs. METHODS: We conducted a compre…
This study aimed to develop and validate a multimodal deep learning model that leverages 2D grayscale ultrasound (US) images alongside readily available clinical data to improve diagnostic performance for ovarian cancer (OC). A retrospectiv…
BACKGROUND: There is evidence for an association between the gut microbiome and endometriosis. However, their causal relationship and the mediating role of lipid metabolism remain unclear. METHODS: Using genome-wide association study (GWAS…
This study aims to construct and validate a nomogram for the differential diagnosis of ovarian endometriosis cyst versus ovarian cystadenoma. We retrospectively studied the clinical characteristics of patients with ovarian endometriosis cys…
Abstract Objective This study aimed to identify and analyze potential signatures of pyroptosis-related genes in EMs. Methods Transcriptomic datasets related to endometriosis were retrieved from the GEO databases (GSE7305, GSE7307, and GSE11…
Background: Determine potential triggers for ovarian endometriosis recurrence to provide individualized long-term management and follow-up for improved patient outcomes. Methods: Relevant data were acquired through systematic retrieval from…
BACKGROUND: In central precocious puberty (CPP), the pulse secretion and release of gonadotropin-releasing hormone (GnRH) are increased due to early activation of the hypothalamic-pituitary-gonadal axis, resulting in developmental abnormali…
Intestinal obstruction caused by the invasion of endometriosis on intestinal walls is rarely reported, and it is difficult to make timely and accurate diagnosis in clinical practice. Herein, we report a rare case of acute intestinal obstruc…