Joseph S. Sanfilippo
ORCID: 0000-0002-6766-6080
· 29 papers in corpus
A study using a Sprague-Dawley rat model was designed to correlate morphologic and intracellular steroid receptor alteration with danazol therapy. One uterine horn was removed for cytoplasmic estrogen receptor analysis following four to eig…
Sprague-Dawley rats with estrous cycles were exposed to danazol (Danocrine) at a single dose of 10 mg/kg for either 6 or 24 hours, or daily until a pattern of no cycles (6 days) was noted on vaginal smears. The animals were individually hou…
The synthetic androgen danazol, is an isoxazol derivative of ethisterone. It is utilized in the treatment of endometriosis, fibrocystic breast disease, and has a potential use as a contraceptive. A study was designed to evaluate the ultrast…