Laura Melado

OBJECTIVE: The objective of this study is to evaluate the effectiveness of prolonged GnRH agonist (GnRH-a) suppression combined with letrozole and intensive luteal phase support in a patient with severe adenomyosis undergoing frozen-thawed …

BACKGROUND: Adenomyosis negatively impacts fertility treatment outcomes by lowering clinical pregnancy rates, reducing live birth rates, and increasing miscarriage rates following in vitro fertilization. Hormonal suppression therapy has eme…

INTRODUCTION: Anti-Müllerian Hormone (AMH) and antral follicle count (AFC) are commonly used markers of ovarian reserve, yet their predictive accuracy in patients with low ovarian reserve remains limited. This study aimed to evaluate whethe…

BackgroundInhibin B (InhB) is secreted by granulosa cells and reflects early follicular activity. While anti-Müllerian hormone (AMH) and antral follicle count (AFC) are established ovarian reserve markers, the role of bioavailable inhibin B…

As a chronic inflammatory disease, endometriosis generates fibrosis and anatomic distortion, which add extra-challenges to assisted reproductive technology cycles and requires a personalized approach. Patients with endometriomas have signif…

BACKGROUND: In a global effort to assess expert perspectives on the use of recombinant gonadotropins, recombinant human luteinizing hormone (r-hLH) and recombinant human follicle-stimulating hormone (r-hFSH), a consensus meeting was held in…

A rise in serum progesterone in the late follicular phase is a well described adverse effect of ovarian stimulation for IVF/ICSI. Previous data suggest, that enhanced gonadotropin stimulation causes progesterone elevation and the incidence …

Luteal phase support is becoming a highly personalized treatment based on each stimulation protocol and patient characteristics. After the application of human chorionic gonadotrophin (hCG) for final oocyte maturation, the vaginal route for…

CONTEXT: The widespread distribution of the Vitamin D (VitD) receptor in reproductive tissues suggests an important role for VitD in human reproduction. The assessment of patient´s VitD is based on the 25-hydroxyvitamin D (25(OH)D) metaboli…

Resumen Presentamos el caso de una paciente con endometriosis infiltrativa profunda, previamente intervenida de endometriosis ovarica, y su manejo posterior. La clinica de la paciente fue el indicador principal de la progresion de la enferm…