Susanne Tranguch

ORCID: 0000-0001-9496-7260 · 4 papers in corpus
article 2010
·doi:10.1093/humrep/de.25.s1.242

Introduction: Endometriosis, defined as the growth of endometrial tissue outside \nthe uterine cavity is a common gynaecological disorder affecting 10-15% \nof women in their reproductive years. It is a major clinical problem causing in- \n…

2010
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.1009324107

Immunophilin FK506-binding protein 52 (FKBP52) is a cochaperone that binds to the progesterone receptor (PR) to optimize progesterone (P(4))-PR signaling. We recently showed that Fkbp52-deficient (Fkbp52(-/-)) mice have reduced uterine PR r…

article 2008
The American Journal of Pathology ·doi:10.2353/ajpath.2008.080527

Endometriosis is a common gynecological disease that affects approximately 10% of women of childbearing age. It is characterized by endometrial growth outside the uterus and often results in inflamed lesions, pain, and reduced fertility. Al…

other 2007
The Journal of clinical investigation ·doi:10.1172/JCI31622

Immunophilin FKBP52 serves as a cochaperone to govern normal progesterone (P(4)) receptor (PR) function. Using Fkbp52(-/-) mice, we show intriguing aspects of uterine P(4)/PR signaling during pregnancy. Implantation failure is the major phe…