Insa Winzenborg

ORCID: 0000-0003-4015-7451 · 8 papers in corpus · active 2018-2022

Study types

  • article 5
  • other 2
  • review 1

Condition tags

  • endometriosis 7
  • dysmenorrhea 1
  • chronic_pelvic_pain 1
article 2022
·doi:10.1111/bcp.15440

AIM: Elagolix, a gonadotropin-releasing hormone receptor antagonist, was recently approved for heavy menstrual bleeding associated with uterine fibroids (UF, Oriahnn) at a dose of 300 mg twice daily (BID) in combination with add-back therap…

other 2021
CPT: pharmacometrics & systems pharmacology ·doi:10.1002/psp4.12570

Selection of a personalized dose for an individual patient can be informed by the patient's preferences, translated as weights on each of the clinically relevant safety and efficacy drug attributes, based on results from a brief patient pre…

article 2021
Clinical pharmacokinetics ·doi:10.1007/s40262-021-01096-w

BACKGROUND AND OBJECTIVES: Elagolix is an orally active, gonadotropin-releasing hormone receptor antagonist approved for the management of endometriosis-associated pain and heavy menstrual bleeding associated with uterine fibroids. Elagolix…

article 2021
Clinical and translational science ·doi:10.1111/cts.13040

Abstract Elagolix is a novel, oral gonadotropin‐releasing hormone receptor antagonist indicated for the management of moderate to severe pain associated with endometriosis and heavy menstrual bleeding associated with uterine fibroids. Consi…

review 2020
Clinical pharmacokinetics ·doi:10.1007/s40262-019-00840-7

The clinical pharmacology of elagolix was extensively evaluated in clinical studies in healthy subjects and in women with endometriosis. Elagolix pharmacokinetics (PK) show significant population variability, however they are minimally affe…

other 2020
CPT: pharmacometrics & systems pharmacology ·doi:10.1002/psp4.12545

Elagolix is an oral gonadotropin-releasing hormone antagonist approved by the US Food and Drug Administration (FDA) for the management of moderate-to-severe pain associated with endometriosis and in combination with estradiol/norethindrone …

article 2020
CPT: pharmacometrics & systems pharmacology ·doi:10.1002/psp4.12560

Elagolix is a novel oral gonadotropin releasing hormone receptor antagonist, that can suppress estradiol in a dose‐dependent manner. It is indicated for management of moderate‐to‐severe pain associated with endometriosis. A population expos…

article 2018
Clinical pharmacokinetics ·doi:10.1007/s40262-018-0629-6