Nardone A

ORCID: 0000-0003-3277-1101 · 4 papers in corpus
2025
Tamoxifen induces PI3K activation in uterine cancer.
Nature genetics ·doi:10.1038/s41588-025-02308-w

Mutagenic processes and clonal selection contribute to the development of therapy-associated secondary neoplasms, a known complication of cancer treatment. The association between tamoxifen therapy and secondary uterine cancers is uncommon …

review 2020
Bisphenol A: an emerging threat to female fertility
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-019-0558-8

Bisphenol-A (BPA) has been reported to be associated to female infertility. Indeed, BPA has been found to be more frequently detected in infertile women thus leading to hypothesize a possible effect of BPA on natural conception and spontane…

review 2020
Smoke, alcohol and drug addiction and female fertility
Reproductive biology and endocrinology : RB&E ·doi:10.1186/s12958-020-0567-7

BACKGROUND: Considerable interest has been gathered on the relevant impact of preventable factors, including incorrect lifestyle and unhealthy habits, on female fertility. Smoking, alcohol and addictive drugs consumption represent a major c…

2016
FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer.
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.1612835113

Forkhead box protein A1 (FOXA1) is a pioneer factor of estrogen receptor α (ER)-chromatin binding and function, yet its aberration in endocrine-resistant (Endo-R) breast cancer is unknown. Here, we report preclinical evidence for a role of …