Lijuan Chen

OBJECTIVE: Limited evidence exists on the safety of inactivated COVID-19 vaccines and the optimal vaccination timing for women undergoing in vitro fertilization-frozen embryo transfer (IVF-FET). This study aims to examine the associations b…

Endometriosis is a common disease among women of childbearing age, and endoplasmic reticulum stress (ERS), a response involved in regulating protein homeostasis, has been linked to its pathogenesis. To identify ERS-related hub genes, this s…

Abstract Background Numerous investigations have demonstrated the implication of endoplasmic reticulum stress (ERS) in the etiology of endometriosis. Employing bioinformatics methodologies, we conducted an analysis to ascertain the particip…

Regulated cell death (RCD) represents a distinct mode of cell demise, differing from accidental cell death (ACD), characterized by specific signaling cascades orchestrated by diverse biomolecules. The regular process of cell death plays a c…

BACKGROUND: Uterine contractions may interfere with embryo implantation in assisted reproductive technology. To reduce these contractions and improve success rates, the oxytocin antagonist atosiban has been suggested for administration duri…

BACKGROUND: Endometriosis, a gynecological disease that affects up to 10% of women, is a major cause of pain and infertility. Deregulation of the epigenome is accountable for the onset and progression of endometriosis, although its exact me…

Gene expression and posttranscriptional regulation can be strongly influenced by epigenetic modifications. N6-methyladenosine, the most extensive RNA modification, has been revealed to participate in many human diseases. Recently, the role …

IMPORTANCE: There is a lack of information regarding the need to postpone conception after COVID-19 vaccination. OBJECTIVE: To investigate the time interval between the first dose of inactivated COVID-19 vaccine and in vitro fertilization …

OBJECTIVE: Predictive models of the cumulative live birth (CLB) in women undergoing in vitro fertilization (IVF) treatment are limited. The aim of this study was to develop and validate a nomogram for the CLB in women undergoing the first I…

Endometriosis is an estrogen-dependent gynecological disease primarily affecting women of childbearing age, which gives rise to pelvic pain calling for multiple operations, and sometimes leading to infertility. However, the etiology of endo…

Endometriosis (EMS) is a gynecologic disorder associated with infertility and characterized by the endometrial-type mucosa outside the uterine cavity. Currently available treatment modalities are limited to undesirable effects. Thus, in the…

Abstract Background: Intriguingly, microRNA-20a (miR-20a) has been recently witnessed to be involved in the pathogenesis of endometriosis (EMS) but the molecular mechanism controlled by miR-20a is to be undefined. The present study is desig…

Abstract The authors have withdrawn this preprint from Research Square

BACKGROUND: In premenopausal women, endocrine adjuvant therapy for breast cancer primarily consists of tamoxifen alone or with ovarian suppressive strategies. Toremifene is a chlorinated derivative of tamoxifen, but with a superior risk-ben…

Objective To observe the clinical efficacy of Sanjie Zhentong Capsule in treating endometriosis following laparoscopic operation. Methods Ninety-seven subjects were randomized into two groups: treatment group in which 52 cases were treated …