Mastenbroek S

Study questionDo parental characteristics and treatment with ART affect perinatal outcomes in singleton pregnancies?Summary answerBoth parental and ART treatment characteristics affect perinatal outcomes in singleton pregnancies.What is kno…

BackgroundIn vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI) treatments conventionally consist of a fresh embryo transfer, possibly followed by one or more cryopreserved embryo transfers in subsequent cycles. An alterna…

Study questionIs IVF with frozen-thawed blastocyst transfer (freeze-all strategy) more effective than IVF with fresh and frozen-thawed blastocyst transfer (conventional strategy)?Summary answerThe freeze-all strategy was inferior to the con…

BackgroundIn in vitro fertilisation (IVF) with or without intracytoplasmic sperm injection (ICSI), selection of the most competent embryo(s) for transfer is based on morphological criteria. However, many women do not achieve a pregnancy eve…

PurposeThe purpose of this paper is to study whether human preimplantation embryos regulate endometrial stromal cell (hESC) migration.MethodsPrimary hESCs were isolated from fertile patients undergoing hysterectomy for benign conditions (ut…

BackgroundIn general, in vitro fertilisation (IVF) or intracytoplasmic sperm injection (ICSI) implies a single fresh and one or more frozen-thawed embryo transfers. Alternatively, the 'freeze-all' strategy implies transfer of frozen-thawed …

Study questionDoes the addition of a low-quality embryo in fresh Day 3 double embryo transfer (DET) affect the ongoing pregnancy rate (OPR) and multiple gestation rate in patients with only one or no high-quality embryos available?Summary a…