De Hullu JA

No ORCID on file · 6 papers in corpus · active 2006-2025
2025
BJOG : an international journal of obstetrics and gynaecology ·doi:10.1111/1471-0528.18075

ObjectiveTo compare menopause-related quality of life (QoL) after risk-reducing salpingectomy (RRS) versus risk-reducing salpingo-oophorectomy (RRSO) until 3 years of post-surgery.DesignA prospective study (TUBA study) with treatment alloca…

2024
JACC. CardioOncology ·doi:10.1016/j.jaccao.2024.09.011

BackgroundPremenopausal risk-reducing salpingo-oophorectomy (RRSO) in women at high familial risk of ovarian cancer leads to immediate menopause. Although early natural menopause is associated with increased cardiovascular disease risk, evi…

2022
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society ·doi:10.1136/ijgc-2022-003911

ObjectiveOvarian cancer is known for its poor prognosis, which is mainly due to the lack of early symptoms and adequate screening options. In this study we evaluated whether mutational analysis in cervicovaginal and endometrial samples coul…

2021
JAMA oncology ·doi:10.1001/jamaoncol.2021.1590

ImportanceMost women with a BRCA1/2 pathogenic variant undergo premature menopause with potential short- and long-term morbidity due to the current method of ovarian carcinoma prevention: risk-reducing salpingo-oophorectomy (RRSO). Because …

2020
International journal of cancer ·doi:10.1002/ijc.32907

Synchronous primary endometrial and ovarian cancers (SEOs) represent 10% of all endometrial and ovarian cancers and are assumed to develop as independent entities. We investigated the clonal relationship between endometrial and ovarian carc…

2006
British journal of cancer ·doi:10.1038/sj.bjc.6603015

To determine the effectiveness of annual gynaecological screening (pelvic examination, transvaginal ultrasound, and CA-125), a prospective cohort study of women at high risk for hereditary ovarian cancer was conducted. Women were offered DN…