Alpoim-Moreira J

No ORCID on file · 2 papers in corpus · active 2023-2026

Study types

  • review 1
review 2026
Exploring the role of epigenetics in the processes related to the development of endometrosis in the mare
The Journal of reproduction and development ·doi:10.1262/jrd.2025-103

Endometrosis is a chronic degenerative condition of the mare endometrium characterized by progressive fibrosis and glandular alterations that impair uterine function and fertility. Its pathogenesis involves persistent inflammation, the acti…

2023
5-Aza-2'-Deoxycytidine (5-Aza-dC, Decitabine) Inhibits Collagen Type I and III Expression in TGF-β1-Treated Equine Endometrial Fibroblasts.
Animals : an open access journal from MDPI ·doi:10.3390/ani13071212

Endometrosis negatively affects endometrial function and fertility in mares, due to excessive deposition of type I (COL1) and type III (COL3) collagens. The pro-fibrotic transforming growth factor (TGF-β1) induces myofibroblast differentiat…