Xinyue Liu

No ORCID on file · 3 papers in corpus
lab-animal 2026
INHBA secreted by cancer-associated fibroblasts promotes cisplatin resistance and malignant progression of ovarian cancer via ENG-mediated suppression of apoptosis and induction of EMT
Journal of translational medicine ·doi:10.1186/s12967-026-08621-0

BACKGROUND: Platinum resistance remains a major cause of treatment failure in ovarian cancer (OC). Cancer-associated fibroblasts (CAFs), key components of the tumor microenvironment, play critical roles in OC progression. Inhibin subunit be…

lab-animal 2025
Knockdown of TOP2A reverses cisplatin resistance in ovarian cancer by inhibiting EMT via ferroptosis mediated by the TP53/GPX4/SLC7A11 axis
Frontiers in immunology ·doi:10.3389/fimmu.2025.1675373

INTRODUCTION: Cisplatin resistance is a major challenge in ovarian cancer therapy, particularly for high-grade serous ovarian cancer (HGSOC). DNA topoisomerase IIα (TOP2A) relates to cancer drug resistance, yet its role and molecular mechan…

review 2025
Recent advances in self-targeting natural product-based nanomedicines
Journal of nanobiotechnology ·doi:10.1186/s12951-025-03092-9

Natural products, recognized for their potential in disease prevention and treatment, have been integrated with advanced nano-delivery systems to create natural product-based nanomedicines, offering innovative approaches for various disease…