Loya-López S

ORCID: 0000-0001-6207-8370 · 3 papers in corpus · active 2022-2023
2023
Neuropilin-1 is essential for vascular endothelial growth factor A-mediated increase of sensory neuron activity and development of pain-like behaviors.
Pain ·doi:10.1097/j.pain.0000000000002970

AbstractNeuropilin-1 (NRP-1) is a transmembrane glycoprotein that binds numerous ligands including vascular endothelial growth factor A (VEGFA). Binding of this ligand to NRP-1 and the co-receptor, the tyrosine kinase receptor VEGFR2, elici…

2022
Distinct Role of Mono-2-ethylhexyl Phthalate in Neuronal Transmission in Rat CA3 Hippocampal Neurons: Involvement of Ion Channels.
Molecules (Basel, Switzerland) ·doi:10.3390/molecules27103082

Mono-(2-ethylhexyl) phthalate (MEHP) is one of the main active metabolites of di-(2-ethylhexyl) phthalate (DEHP). In our previous works, by using rat and Drosophila models, we showed a disruption of neural function due to DEHP. However, the…

2022
Plant and fungi derived analgesic natural products targeting voltage-gated sodium and calcium channels.
Channels (Austin, Tex.) ·doi:10.1080/19336950.2022.2103234

Voltage-gated sodium and calcium channels (VGSCs and VGCCs) play an important role in the modulation of physiologically relevant processes in excitable cells that range from action potential generation to neurotransmission. Once their expre…