Wancheng Yu

No ORCID on file · 1 paper in corpus

lab-animal 2019

Mst1 promotes cardiac ischemia-reperfusion injury by inhibiting the ERK-CREB pathway and repressing FUNDC1-mediated mitophagy

The journal of physiological sciences : JPS ·doi:10.1007/s12576-018-0627-3

Cardiac ischemia-reperfusion (I/R) injury results mainly from mitochondrial dysfunction and cardiomyocyte death. Mitophagy sustains mitochondrial function and exerts a pro-survival effect on the reperfused heart tissue. Mammalian STE20-like…