Vafaei S

No ORCID on file · 5 papers in corpus · active 2014-2026

Study types

  • other 3
  • article 1

Condition tags

  • endometriosis 1
other 2026
Phthalate Metabolite, Mono(2-Ethyl-5-Hydroxyhexyl) Phthalate (MEHHP), Promotes Uterine-Fibroid-Associated Phenotypes in Myometrial Stem Cell-Derived 3D Organoids
Environmental toxicology ·doi:10.1002/tox.70046

This study investigates how phthalate exposure contributes to uterine fibroid (UF) development by studying the effects of the Mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP), a metabolite of Di(2-ethylhexyl) phthalate, on myometrial stem ce…

other 2025
Utilising Human Myometrial and Uterine Fibroid Stem Cell-Derived Three Dimentional Organoids as a Robust Model System for Understanding the Pathophysiology of Uterine Fibroids
Cell proliferation ·doi:10.1111/cpr.70025

Uterine fibroids (UFs) are the most common benign gynecologic tumours affecting women of reproductive age. This study aims to deepen the understanding of UFs complex aetiology through harnessing the power of 3D organoid models derived from …

article 2023
Prevention of uterine fibroids: Molecular mechanisms and potential clinical application
Journal of endometriosis and uterine disorders ·doi:10.1016/j.jeud.2023.100018

• Uterine fibroids are the most common benign tumor to women of reproductive age with no clear pathomechanism. • Current medical therapies are designed to blunt the stimulatory effects of gonadal steroid hormones on uterine fibroids growth.…

2015
Lipopolysaccharide- and Lipoteichoic Acid-mediated Pro-inflammatory Cytokine Production and Modulation of TLR2, TLR4 and MyD88 Expression in Human Endometrial Cells.
Journal of reproduction & infertility

BackgroundToll-like receptor (TLR)-mediated inflammatory processes are supposed to be involved in pathophysiology of spontaneous abortion and preterm labor. Here, we investigated functional responses of human endometrial stromal cells (ESCs…

other 2014
Menstrual blood-derived stromal stem cells from women with and without endometriosis reveal different phenotypic and functional characteristics
Molecular human reproduction ·doi:10.1093/molehr/gau044

Retrograde flow of menstrual blood cells during menstruation is considered as the dominant theory for the development of endometriosis. Moreover, current evidence suggests that endometrial-derived stem cells are key players in the pathogene…