Darb-Esfahani S

No ORCID on file · 6 papers in corpus · active 2008-2019

Study types

  • article 2

Condition tags

  • endometriosis 2
  • die_deep_infiltrating 1
2019
Discovery and Validation of Novel Biomarkers for Detection of Epithelial Ovarian Cancer.
Cells ·doi:10.3390/cells8070713

Detection of epithelial ovarian cancer (EOC) poses a critical medical challenge. However, novel biomarkers for diagnosis remain to be discovered. Therefore, innovative approaches are of the utmost importance for patient outcome. Here, we pr…

2017
High-grade ovarian serous carcinoma patients exhibit profound alterations in lipid metabolism.
Oncotarget ·doi:10.18632/oncotarget.22076

Ovarian cancer is a very severe type of disease with poor prognosis. Treatment of ovarian cancer is challenging because of the lack of tests for early detection and effective therapeutic targets. Thus, new biomarkers are needed for both dia…

2016
Accumulated Metabolites of Hydroxybutyric Acid Serve as Diagnostic and Prognostic Biomarkers of Ovarian High-Grade Serous Carcinomas.
Cancer research ·doi:10.1158/0008-5472.can-15-2298

Ovarian cancer is a heterogeneous disease of low prevalence, but poor survival. Early diagnosis is critical for survival, but it is often challenging because the symptoms of ovarian cancer are subtle and become apparent only during advanced…

article 2016
(Partial) Loss of BAF250a (ARID1A) in rectovaginal deep-infiltrating endometriosis, endometriomas and involved pelvic sentinel lymph nodes
Molecular human reproduction ·doi:10.1093/molehr/gaw009

STUDY HYPOTHESIS: Loss of protein BAF250a (ARID1A) expression is present in women with rectovaginal deep-infiltrating endometriosis (DIE) and endometriosis affecting the pelvic sentinel lymph nodes (PSLN). STUDY FINDING: Partial loss of pro…

article 2015
Immunohistochemical Investigation of Metastasis-Related Chemokines in Deep-Infiltrating Endometriosis and Compromised Pelvic Sentinel Lymph Nodes
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719115592711

Endometriosis is a prevalent benign disease, despite sharing several similarities with malignancies, such as the possibility of lymphatic spread. In malignancies, chemokines play a sovereign role in the process of metastasis. Metastasis-rel…

2008
Expression of class I histone deacetylases indicates poor prognosis in endometrioid subtypes of ovarian and endometrial carcinomas.
Neoplasia (New York, N.Y.) ·doi:10.1593/neo.08474

Histone deacetylase (HDAC) inhibitors are an emerging class of targeted cancer therapeutics, and little is known about HDAC expression in gynecologic malignancies. Therefore, we tested the hypothesis whether high-level expression of class 1…